Jennifer Lopez: I've felt abused

Jennifer Lopez's love life has always been in the spotlight. In a new book, the actress and singer says she's learned some important lessons along the way, including "how to take care of myself and know my worth." Here's a look back at Lopez's life and career:

Lopez's big break came in the title role of the biopic "Selena," which catapulted her into the limelight. She brought then-husband Ojani Noa to the Hollywood film premiere in 1995.

Lopez also put a great deal of energy into her music career, which was upstaged in 2000 by this outfit at the Grammys.

Remember when Lopez and Ben Affleck were engaged? The pair attended the 75th Annual Academy Awards at the Kodak Theater in Hollywood in 2003.

Lopez is also a businesswoman with an empire that includes a few fragrance lines. In 2004, she made an appearance at Macy's Herald Square in New York.

Lopez and then-husband Marc Anthony leave the Jennifer Lopez Fall 2005 show during Olympus Fashion Week at Bryant Park in New York.

Lopez and Anthony became parents to twins Max and Emme in 2008.

Lopez attended the Launch of Gucci Children's Collection in 2010 in Beverly Hills.

Lopez hosted an American Music Awards afterparty on November 20, 2011, in West Hollywood, California.

Lopez joined Randy Jackson and Steven Tyler as judges for "American Idol" in 2012. She left after a season, but returned to the show in 2013.

Even while singing and heading her business empire, Lopez has continued to act and in 2012 attended the premiere of her film "What To Expect When You're Expecting" at Grauman's Chinese Theatre in Hollywood.

Lopez performed her hit "On The Floor" in 2011 at the American Music Awards.

Lopez at a post-concert party at the Pure Nightclub at Caesars Palace in 2012 in Las Vegas.

Lopez and actress Cameron Diaz presented the Oscar for makeup at the 84th Annual Academy Awards in 2012.

After her divorce from Anthony, Lopez started dating dancer Casper Smart, who is 18 years her junior. The pair, seen here attending a 2012 event at Planet Dailies & Mixology 101 in Los Angeles, broke up in 2014.

Lopez is also very involved in charity work. In June 2013, she was the recipient of the Humanitarian Award at the fourth annual amfAR Inspiration Gala in New York.

In June 2013 she also received the 2,500th star on the Hollywood Walk of Fame in Los Angeles.

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• Jennifer Lopez opens up about past relationships in new book


• Lopez says she's felt abused in "one way or another"


• She does not say that she was physically abused


• The star says her book represents a journey of self-discovery

(CNN) -- Not all abuse leaves physical scars, and that's a reality Jennifer Lopez is exploring in a new memoir.

The actress and singer has written a book about a period of self-discovery that occurred around the time of her first world tour in 2012. While she intended for the project "to be a fan book, a diary of the years I went on tour," what resulted was a book that helped the star "face a lot," as she tells People magazine.

This is the story of how I discovered the truest love of all. #JLoTrueLove pre-order: http://t.co/2uWXGZd4Yj https://t.co/gBDsocc3hW

— Jennifer Lopez (@JLo) October 29, 2014

One of the things she faces in her memoir are her experiences in past relationships.

"I've never gotten a black eye or a busted lip, but I've felt abused in one way or another: mentally, emotionally, verbally," Lopez writes in the book, titled "True Love."

People magazine notes that the 45-year-old doesn't name her abuser, nor does she say she was physically abused.

Lopez adds that she intentionally doesn't divulge details.

"I would never go into specifics about my relationships, and I don't. But the idea was that I learned something," she says.

Lopez has tied the knot three times, with her most recent marriage, to singer Marc Anthony, ending in 2011 after seven years. Looking back on all of her past relationships, she says she's learned to "take care of myself and know my worth."

"When things are not working out, and you're not being treated in a way that you want to be treated, you have to look at that because it's nobody's fault but yours," Lopez tells People. "You have to take control and you have to set up your own boundaries. You have the power to change it."

Scientists link 60 genes to autism

Genetic research has been used to treat all kinds of disorders and diseases.

• Scientists identify 60 genes with greater than 90% chance of increasing autism risk


• Studies zero in on the exact nature of the genetic mutations that cause the disorder


• This discovery could lead to faster diagnosis and better treatments

(CNN) -- Researchers have found dozens of new genes that may play a role in causing autism, according to two studies published Wednesday in the medical journal Nature.

Scientists identified 60 genes with a greater than 90% chance of increasing a child's autism risk. Previous research has yielded only 11 genes that had been confirmed with this level of certainty.

Though other studies have shown the importance of genetics in the development of autism, experts say these new studies zero in on the exact nature of the genetic mutations that cause the disorder.

The researchers say these genes appear to be clustering around three sets of key biological functions.

The first set focuses on the development of synapses in the brain, which are responsible for all kinds of communication between nerves. The second set is responsible for the creation of genetic instructions, and the third is responsible for DNA packaging within cells.

Each of these functions could have an effect on the individual that would cause the traits commonly associated with autism, according to one of the studies.

Dr. Matthew State, chairman of the Department of Psychiatry at the University of California, San Francisco, and co-author of both studies, believes that the most important thing to take away from the studies is a new knowledge base. Instead of focusing on environmental factors, he says, these studies are focusing on what happens inside of the brain.

This kind of genetic research has been used to treat all kinds of disorders and diseases, State says, but before now had not been applied to psychiatric disorders. Similar genetic studies for childhood leukemia took it from nearly always fatal to a treatable, often curable disease.

"It's the understanding of biology at that level that's helped treatments for cancer. It's something we've been missing in psychiatric disorders in general," State said. "They lay the groundwork for a transformed understanding of the disorder and hopefully a transformation in how we're able to diagnose and treat it."

Autism is a complex disorder, one that has been difficult to treat because it is so poorly understood. By tapping into the genetic foundation of the disorder, scientists theorize, it may be possible to provide more personalized treatment based on a person's own unique gene set.

"I think that if everybody were to be genotyped when they're diagnosed, the more this is studied, the more we'll be able to say what the biological causes are ... and we can target your symptoms with more personalized medicine," said Dan Smith, senior director of neuroscience at the advocacy organization Autism Speaks.

In addition to developing treatments based on a better understanding of the disorder, the study provides hope for the prevention of autism as well. A portion of the genes studied were de novo genes: not passed down from either parent but developed in the egg or sperm shortly before conception. Further studies could determine what environmental factors cause those genes to mutate.

"This is going to begin to give us an opportunity to study the interactions between genes and environment," State said. "The rate of new mutation increases with age, specifically fathers, because a lot of these mutations are in sperm."

State is optimistic about the future and what these two studies will contribute.

"The big difference is that five years ago, we had no idea. When you have no idea, you have no opportunity to think in a systematic or rational way to develop treatment," he said. "We can finally say something really concretely about a large number of genes that contribute to risk."

3, 2, 1 ... what happened?

• Public urged to stay away from rocket debris


• NASA teams checking damage to Wallops Flight Facility


• The International Space Station has plenty of supplies, NASA says

(CNN) -- Teams of investigators were out at daybreak Wednesday examining damage to NASA's Wallops Flight Facility after an unmanned rocket exploded shortly after launch on the Virginia coast, NASA spokeswoman Rachel Kraft told CNN via email. NASA is warning people in the area not to touch debris if they find any.

The Antares rocket, built by NASA contractor Orbital Sciences Corp., and its Cygnus cargo spacecraft "suffered a catastrophic failure" shortly after liftoff Tuesday evening, the company said. The crash caused a huge fire and scattered debris over a large area.

Orbital Sciences told CNN it would issue a statement on the status of the investigation later Wednesday.

What caused the rocket explosion?

How do astronauts shower in space?

NASA-contracted rocket explodes on launch

The cargo module was carrying 5,000 pounds of supplies and experiments meant for the International Space Station.

On what was to be a resupply mission to the International Space Station, an unmanned NASA-contracted rocket exploded seconds after launch Tuesday, October 28, on the coast of Virginia. The launchpad was damaged, but no one was injured.

People who came to Wallops Island, Virginia, to watch the launch walk away after the unmanned rocket, owned by Orbital Sciences Corp., exploded.

The rocket and spacecraft -- which together cost more than $200 million, according to Frank Culbertson, the general manager of Orbital's Advanced Programs Group -- are gone.

The rocket had been set to go up Monday, only to be scrubbed "because of a boat downrange in the trajectory Antares would have flown had it lifted off," according to NASA. Coast Guard spokesman David Weydert said the boat that triggered the postponement was 40 miles offshore. Tuesday, by contrast, seemed perfect. Just before liftoff, NASA reported "100% favorable" weather and "no technical concerns with the rocket or spacecraft being worked."

The Antares rocket, with the Cygnus spacecraft on board, is seen on Launch Pad-0A after the launch attempt was scrubbed on October 27.

The Orb-3 mission's payload fairing (essentially the casing around the spacecraft) was installed on the Antares on October 23.

The payload fairing goes onto the spacecraft. Orbital will lead the investigation of the accident, along with the FAA, with NASA assisting. Among other things, they'll try to collect and examine any debris that can be recovered, review data from the spacecraft before its destruction and look at videos around the launch time.

Unmanned rocket explodes

Raw video of unmanned rocket explosion

Kelly: 'Space flight is a difficult thing'

Official: Rocket explosion tragic but ...

Officials say no one was injured or killed in the explosion, but NASA says debris may be scattered around the launch area and some may have fallen into the ocean.

Rocket explodes in fireball. What happened?

The public is being warned to forget about grabbing up rocket debris as souvenirs. "It had a lot of hazardous materials on board that people should not be looking for or wanting to collect souvenirs over," said Frank Culbertson, a former NASA astronaut and now a manager at Orbital Sciences Corp. "If you find anything that washes ashore in the local area or came down on your farm or in your yard ... definitely do not touch it and keep people away from it."

"There may be a possibility of debris washing up onto some of the beaches into some of the areas surrounding the island," Bill Wrobel, director of NASA's Wallops Flight Facility, said a news conference Tuesday. If people do find any debris, they're being urged to call NASA at 757-824-1295.

NASA says teams started assessing damage to Wallops at daylight Wednesday.

"Damage was contained to kind of the south end of Wallops Island," Wrobel said. "That's predominately where many of the pieces came down."

Opinion: Rockets blow up; we move on

'You see a big fireball'

The rocket lifted off at 6:22 p.m. ET, but about six seconds after launch, there was an explosion and the rocket fell to the ground, engulfed in a huge fireball.

It seemed to be going perfectly when Ed Encina saw the launch brighten up the sky from his vantage point about 3 miles away.

"And then, all of a sudden, you see a big fireball," said Encina, a Baltimore Sun reporter.

He recalled a loud boom that caused "your feet (to) shake a little bit," as well as flames enveloping a roughly 100-yard area around the launchpad in a marshy area with brush.

CNN iReporter Dymetria Sellers, who watched from a drawbridge because the NASA visitors station was full, recalled a "breathtakingly beautiful" sight when the rocket ascended, followed by mass confusion as flames lit up the early nighttime sky moments later.

"About 30 seconds later, we could hear and feel two booms reach us, and it was apparent the rocket had exploded," she said.

Did you witness the rocket explosion? Please share your images

Mark Kelly, a former NASA astronaut, said such a colossal fire was to be expected after the launch failure.

"It takes a lot of propellant to take a spacecraft of that size moving 25 times the speed of sound," Kelly told CNN, explaining how fast the rocket should have gone on its way to the space station. "So when it fails, it's usually pretty catastrophic."

Orbital Sciences will lead the investigation into the explosion. NASA and the Federal Aviation Administration will assist.

"What we know so far is pretty much what everybody saw on the video," Culbertson said. "The ascent stopped, there was some, let's say disassembly, of the first stage, and then it fell to Earth. ... We don't really have any early indications of exactly what might have failed, and we need some time to look at that."

They'll examine debris and review video of the launch and telemetry from the spacecraft. "We have reams and reams of data that comes down from the rocket during launch," Culbertson said.

Payload included student experiments

The cargo included crew supplies, hardware for the space station, spacewalk equipment and several experiments designed by students. No classified payloads were on board the spacecraft, said Kraft, the NASA spokeswoman.

One experiment from Duchesne Academy of the Sacred Heart in Houston would have tested how pea shoots grow in space. The school said on its website that students, parents and teachers were shocked and disappointed by the explosion, but that it wasn't a total loss.

"The amount of learning that occurred as a result of being part of this program through the Center for the Advancement of Science in Space (CASIS) is incredible and the students and their teachers ... should always be proud of this accomplishment," the school said.

Also lost in the blast was a study called Drain Brain, which was designed to help learn more about blood flow in space, and an experiment called Meteor, which may have helped find previously undetected meteor showers.

The cargo also included more than 1,300 pounds of food for the space station. NASA four to six months' worth of food is stashed on board, so there is no worry the crew will go hungry.

Also, a Russian Progress resupply vehicle arrived at the space station Wednesday. And SpaceX is scheduled to take up supplies in December.

"The station is in great shape; the crew is in good shape," said Mike Suffredini, the space station's program manager.

Opinion: Don't overreact to rocket explosion

CNN's Greg Botelho, Chandler Friedman, Kevin Conlon, Jareen Imam and Dave Alsup contributed to this report.